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Applied Network Science
Fig. 6 | Applied Network Science

Fig. 6

From: An efficient weighted network centrality approach for exploring mechanisms of action of the Ruellia herbal formula for treating rheumatoid arthritis

Fig. 6

Herb-compositive compound-putative target-RA known target-PPI network. A Herb-putative target-RA known targets network; B Imbalance multi-level network of herb-compositive compound-putative target-RA known target-PPI network. Edges: interactions among the two herbs, compositive compounds, putative targets, RA known therapeutic targets and Other Human proteins’ PPI Network. Yellow square nodes: Ruellia prostrata (RP) and Ruellia bignoniiflora (RB) herbs; green round nodes: RP–RB compositive compounds; red round nodes: putative targets; blue round nodes: RA known therapeutic targets; purple round nodes: Other Human proteins. Nodes with yellow borders are major components with corresponding high weighted centrality scores

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