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Fig. 5 | Applied Network Science

Fig. 5

From: Testing biological network motif significance with exponential random graph models

Fig. 5

Alon E. coli regulatory network. (a) Node size is proportional to in-degree. (b) Node size is proportional to out-degree. Self-regulating operons are depicted as filled (red) circles. In (a) there appears to be a small set of high in-degree nodes and a much larger set of smaller in-degree nodes, while in (b) the out-degree of the nodes appears to be much more evenly distributed. The hypothesis we might make from (a), that there is centralization on in-degree, is confirmed by the ERGM results. This same model finds no support for the hypothesis we might make from (b), that there is a tendency against centralization on out-degree

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