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Table 4 Performance ceiling on IUPHAR with optimal parameters

From: LPbyCD: a new scalable and interpretable approach for Link Prediction via Community Detection in bipartite networks

Approach

CD method/measure

Optimal parameters

Performance

Running time, sa

AUC

AUPR

Baseline

eta = 0.2, beta = 0.7

0.57

b

\(11.9\times 8137\)c

LPbyCD

Spectral part./\(JC_{CC}\)

m = 400, defaultd

0.74

0.01

3477.8

 

Spectral part./\(JC_{NC}\)

m = 0, w/o threshold

0.85

0.01

2484.91

 

Louvain/\(JC_{CC}\)

Resolution = 0.1

0.61

0.10

5263.97

 

Louvain/\(JC_{NC}\)

Resolution = 0.8

0.82

0.02

2702.62

  1. a for 1 fold in average
  2. b taken from Koptelov et al. (2018), where AUPR was not reported
  3. c must be run for each drug
  4. d without thresholding optimization