Table 1 Standard parameter values used in the study
From: A master stability function approach to cardiac alternans
| Â | Definition | Value |
|---|---|---|
T | Temperature | 308 K |
F | Faraday’s constant | 96.4867 C/mmol |
R | Gas constant | 8.314 J/K mol |
Na o | External sodium concentration | 140 mM |
Ca o | External calcium concentration | 1.8 mM |
vs/vi | Subsarcolemmal/cell volume | 0.1 |
v up | Uptake strength | 270 μM/s |
\(\bar {I}_{\textrm {NaCa}}\) | Strength of the NaCa exchanger | 105μM/s |
K mNa | Constant from the 1994 Luo-Rudy model | 87.5 mM |
K mCa | Constant from the 1994 Luo-Rudy model | 1.38 mM |
P Ca | Constant from the 1994 Luo-Rudy model | 5.4Ă—10−4 cm/s |
i Ca | Flux constant | 11000 μmol/C cm |
γ o | Constant from the 1994 Luo-Rudy model | 0.341 |
g | Release current strength | 3.5Ă—104 sparks/ μM |
k | Release slope | 11.3 s −1 |
Ï„ r | Average spark life time | 20 ms |
Ï„ a | Relaxation time of cu to cj | 50 ms |
Ï„ s | Submembrane diffusion time constant | 10 ms |
β s | Buffering constant for cs | 0.5 |
β i | Buffering constant for ci | 0.01 |