Table 11 Comparison of the modular structure of the Main network
From: Guideline for comparing functional enrichment of biological network modular structures
Parameter | Alternative | Mixed | Rewired |
|---|---|---|---|
No. Nodes | Lesser | Lesser | Equal |
No. Edges | Greater | Lesser | Equal |
Node Similarity (J) | 0.03 | 0.32 | 1.00 |
Edge Similarity (J) | 0.00 | 0.26 | 0.37 |
Modularity (Q) | Greater | Greater | Lesser |
Module Topological Similarity | SimScoreedge=0.01 | SimScoreedge=0.30 | nmi=0.63 |
Network Functional Similarity (J) | 0.50 | 0.30 | 0.88 |
Main modules with functionally similar counterparts | 0/20 | 7/20 | 15/20 |
Functional Euclidian Distance | 10.20 | 8.77 | 6.00 |