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Table 7 Statistical analysis of optimal clustering configurations using selected ASD outcome measures: for kNN2 graphs without node reassignment

From: Applications of node-based resilience graph theoretic framework to clustering autism spectrum disorders phenotypes

Cluster (size)

ABC overall

RBS R overall

ADOS CSS

Vineland composite score

Overall IQ

PPVTA 4A

Epilepsy

kNN 2 VAT k=2

 

C0 (2072)

47.01(26.1)

27.74(17.9)

7.38(1.7)

73.99(12.0)

83.50(27.1)

87.51(27.9)

2.27%

C1 (506)

45.66(25.3)

25.01(16.1)

7.69(1.6)

70.47(12.9)

69.09(28.5)

71.46(29.3)

2.77%

S (102)

46.03(21.6)

26.89(15.1)

7.52(1.5)

73.71(9.6)

81.75(23.2)

77.94(35.1)

0.98%

ANOVA p-value

0.295

0.002

< 0.001

< 0.001

< 0.001

< 0.001

 

Eta-squared (η2)

0

0.004

0.005

0.013

0.042

0.049

 

kNN 2 Integrity k=5

 

C0 (1096)

41.02(22.0)

23.30(14.8)

7.19(1.7)

78.36(10.3)

94.63(20.6)

97.91(22.2)

1.37%

C1 (430)

67.76(24.6)

43.94(19.2)

7.61(1.7)

70.22(9.7)

78.58(23.8)

83.02(25.0)

1.86%

C2 (402)

41.49(23.8)

24.42(15.8)

7.57(1.7)

73.88(11.3)

78.34(24.3)

79.36(25.4)

2.00%

C3 (384)

32.54(18.1)

18.99(10.5)

7.47(1.6)

75.41(10.6)

82.90(21.9)

84.73(23.3)

2.09%

C4 (350)

59.67(27.2)

30.74(17.2)

7.83(1.5)

58.58(9.9)

40.55(19.3)

43.70(22.9)

6.03%

S (18)

56.33(22.6)

32.50(15.0)

7.72(1.9)

69.33(14.2)

68.78(36.4)

65.56(46.7)

11.1%

ANOVA p-value

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

 

Tukey HSD (NSa)

C0:C2

C0:C2

C1:C2,C3,C4; C2:C3,C4

C2:C3

C1:C2

C1:C2,C3

 

Eta-squared (η2)

0.211

0.210

0.019

0.279

0.383

0.329

 

kNN 2 Tenacity k=5

 

C0 (741)

47.01(26.1)

29.38(18.8)

7.46(1.6)

73.25(9.9)

81.26(22.4)

83.63(23.3)

2.30%

C1 (951)

41.23(22.4)

22.84(14.8)

7.08(1.7)

78.68(10.5)

95.58(20.3)

99.41(21.6)

1.26%

C2 (591)

45.06(26.3)

25.66(17.3)

7.61(1.7)

71.44(13.3)

70.86(28.5)

72.95(29.9)

2.54%

C3 (216)

68.07(25.8)

41.92(17.0)

8.56(1.5)

68.76(8.9)

75.79(27.1)

80.39(28.1)

2.33%

C4 (172)

54.72(25.2)

28.90(14.0)

7.35(1.4)

56.13(8.9)

36.17(16.6)

37.64(18.6)

7.60%

S (9)

46.22(19.4)

23.56(15.7)

7.78(1.0)

72.67(11.8)

79.00(23.5)

81.88(34.3)

0%

ANOVA p-value

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

 

Tukey HSD (NS ‡)

C0:C2

C4:C0,C2

C0:C2,C4 C4:C1,C2

None

C2:C3

C0:C3

 

Eta-squared (η2)

0.078

0.086

0.054

0.214

0.298

0.270

 
  1. aNS: implies pairs for which Tukey HSD test was not significant. S is not included in the ANOVA, Tukey, and Eta-squared analyses
  2. The mean and standard deviation values are presented for each measure)