A spatially heterogeneous network-based metapopulation software model applied to the simulation of a pulmonary tuberculosis infection

Applied Network Science

Table 6 T-cell event parameters used for experiments, unless specified in the text

Parameter	Description	Value (per day)	Source
K	Rate of destruction of M_I by T_A	1.3	(Marino and Kirschner 2004)
H _K	Half-sat value for destruction of M_I by T_A	0.5	(Marino and Kirschner 2004)
\(A_{T\_MI}\)	Rate of T-cell activation by antigen presentation by M_I	1E-5	Estimated
\(A_{T\_DCM}\)	Rate of T-cell activation by antigen presentation by DC_M	1E-5	(Marino and Kirschner 2004)
D _TN	Rate of death of T_N	0.102	(Marino and Kirschner 2004)
D _TA	Rate of death of T_A	0.3333	(Marino and Kirschner 2004)
R _T	Standard rate of recruitment of T_N into lymph	1000	(Marino and Kirschner 2004)
\(E_{T\_DCM}\)	Enhanced rate of recruitment of T_N into lymph due to DC_M	0.1	(Marino and Kirschner 2004)
\(E_{T\_MI}\)	Enhanced rate of recruitment of T_N into lymph due to M_I	0.1	Estimated
T _T	Rate of translocation of T_A along BloodEdge (lymph to lung)	0.6	(Marino and Kirschner 2004)