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Table 5 Macrophage event parameters used for experiments, unless specified in the text

From: A spatially heterogeneous network-based metapopulation software model applied to the simulation of a pulmonary tuberculosis infection

Parameter Description Value (per day) Source
A M Rate of activation/deactivation of MR by TA 0.3 (Marino and Kirschner 2004)
H MA Half-sat value for activation of MR by TA 5E2 Estimated
I Rate of macrophage infection by BER and BED 0.4 (Marino and Kirschner 2004)
H MI Half-sat value for macrophage infection 1E6 (Marino and Kirschner 2004)
D MR Death rate of MR 0.01 (Marino and Kirschner 2004)
D MA Death rate of MA 0.01 (Marino and Kirschner 2004)
D MI Standard death rate of MI 0.01 (Marino and Kirschner 2004)
B Rate of bursting of MI due to BIM 0.25 (Marino and Kirschner 2004)
\(R_{M\_lung}\) Standard rate of recruitment of MR into lung 400 (Wigginton and Kirschner 2001)
\(R_{M\_lymph}\) Standard rate of recruitment of MR into lymph 53.465 (Marino et al. 2010)
\(E_{M\_MI}\) Enhanced rate of recruitment of MR into lung by MI 0.0056 (Marino and Kirschner 2004)
\(E_{M\_MA}\) Enhanced rate of recruitment of MR into lung by MA 0.04 (Marino and Kirschner 2004)
T M Rate of translocation of MI along LymphEdge (lung to lymph) 0.25 Estimated