Skip to main content

Table 1 Subpopulation compartments used in TBMetapopPy

From: A spatially heterogeneous network-based metapopulation software model applied to the simulation of a pulmonary tuberculosis infection

Cell type

Name

Symbol

Description

Bacteria

Bacterium extracellular replicating

B ER

Bacteria present on the alveolar tissue which have a high replication metabolism

 

Bacterium extracellular dormant

B ED

Bacteria present on the alveolar tissue which have a low replication metabolism

 

Bacterium intracellular macrophage

B IM

Bacteria which are present inside infected macrophages (MI)

 

Bacterium intracellular macrophage

B ID

Bacteria which are present inside mature dendritic cells (DCM)

Macrophages

Macrophage resting

M R

Macrophages in a natural state

 

Macrophage activated

M A

Macrophages which have been activated by the immune system to increase cytotoxic capabilities

 

Macrophage infected

M I

Macrophages which have internalised, and become infected by, bacteria

Dendritic cells

Dendritic cell immature

D C I

Dendritic cells in a natural, immature state

 

Dendritic cell mature

D C M

Dendritic cells which have come into contact with bacteria and have matured into an antigen-presenting state

T-cells

T-cell naïve

T N

T-cells in a natural, unactivated state

 

T-cell activated

T A

T-cells which have been activated by antigen presentation