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Table 1 Subpopulation compartments used in TBMetapopPy

From: A spatially heterogeneous network-based metapopulation software model applied to the simulation of a pulmonary tuberculosis infection

Cell type Name Symbol Description
Bacteria Bacterium extracellular replicating B ER Bacteria present on the alveolar tissue which have a high replication metabolism
  Bacterium extracellular dormant B ED Bacteria present on the alveolar tissue which have a low replication metabolism
  Bacterium intracellular macrophage B IM Bacteria which are present inside infected macrophages (MI)
  Bacterium intracellular macrophage B ID Bacteria which are present inside mature dendritic cells (DCM)
Macrophages Macrophage resting M R Macrophages in a natural state
  Macrophage activated M A Macrophages which have been activated by the immune system to increase cytotoxic capabilities
  Macrophage infected M I Macrophages which have internalised, and become infected by, bacteria
Dendritic cells Dendritic cell immature D C I Dendritic cells in a natural, immature state
  Dendritic cell mature D C M Dendritic cells which have come into contact with bacteria and have matured into an antigen-presenting state
T-cells T-cell naïve T N T-cells in a natural, unactivated state
  T-cell activated T A T-cells which have been activated by antigen presentation