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Applied Network Science
Fig. 9 | Applied Network Science

Fig. 9

From: A spatially heterogeneous network-based metapopulation software model applied to the simulation of a pulmonary tuberculosis infection

Fig. 9

The overall bacterial growth (BER, BED, BIM and BID) upon a multiple patch topology with different routes of bacterial dissemination. Patches are grouped by spatial location (base, middle and apex). Line is mean, shading is standard deviation. All simulations use event parameters as per Tables 3, 4, 5 and 6. a shows the results of a network where translocation within the lung can only occur within the same lobe (i.e. small-distance translocation). b shows the effects of completely removing translocation within the lung. c shows the effects of removing translocation of bacteria via the lymphatics and bloodstream back to the lung. In all cases, removing options of translocation results in a similar pattern of growth to when all methods are viable (Fig. 7)

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