Complex network analysis of thermostable mutants of Bacillus subtilis Lipase A

Applied Network Science

Table 2 New contacts in PCNs contribute to the stabilizing factors in mutant proteins

	M1	M2	M3	M4	M5	M6
Loop stabilization	√√	√√√	√√	√√	√√	√√√
Secondary Structure Stabilization	√√	√√	√√	√√	√√	√√
Termini stabilization	√	√	√	√	√	√
Active site Rigidity	√√	√√	√√	√√	√√	√√

Ticks correspond to the number of contacts involved in each factor: √ for 0–6 contacts; √√ for 6–12 contacts; and √√√ for 12–18 contacts